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The Brookdale Foundation Group

300

Frank W. Burr Blvd

Suite 13

Teaneck, NJ

07666

 

Phone:

201-836-4602

 

Fax:

201-836-4342

 

Jürgen Winkler, MD

Jürgen Winkler studied human medicine at the Albert-Ludwigs-University in Freiburg, Germany and the Louis Pasteur University Straßburg, France. His residency in Neurology was completed at the Heinrich-Heine-University Düsseldorf, the Julius-Maximilians-University Würzburg and the University Regensburg, all in Germany. During his time at the University of California San Diego he obtained an Assistant Adjunct Professorship of Neurosciences and was National Brookdale Fellow of the Brookdale Foundation in New York. After his return to Germany 1999, he was professor for clinical neurobiology and leading attending neurologist, head of the stroke-unit and intensive care-unit at the Department of Neurology of the University of Regensburg. After a one-year period as chief of the Department of Neurology at the Municipal Hospital Landshut he moved to the University Hospital Erlangen in September 2008 as head of the Division of Molecular Neurology (http://www.molekulare-neurologie.uk-erlangen.de/)

Jürgen Winklers research focuses on neurodegenerative diseases and the development of neuroregenerative strategies. Main focus of his scientific research is to understand the biology of adult neural stem cells in the brain and to explore this potential as source for cellular regeneration. From the clinical perspective, he leads the outpatient clinic for movement disorders. Besides cellular plasticity in the adult brain the Division has an emphasis on proteinaggregation in different neurodegenerative disorders, in particular synucleinopathies.

The present projects are funded by the Federal Ministry of Education and Research (http://www.bmbf.de/en/index.php) and the Bavarian State Ministry of Sciences, Research and the Arts (http://www.bayfor.org/de/geschaeftsbereiche/forschungsverbuende/welt-des-lebens/forneurocell.html)

Dr. Winkler’s Brookdale project explored the functional consequences of genetically engineered neuronal precursor cells in animals with immunotoxin-induced lesions of the cholinergic basal forebrain system. This continued the development of an animal model for testing potential therapeutic modalities designed to treat cognitive disorders. Finally, practical information regarding the transplantation of neuronal precursor cells that may be applicable to the design and conduct of future human clinical trials was gained.

Brookdale Fellow Class of 1996

11/09