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The Brookdale Foundation Group

300

Frank W. Burr Blvd

Suite 13

Teaneck, NJ

07666

 

Phone:

201-836-4602

 

Fax:

201-836-4342

 

Albert Shaw, MD, PhD

Dr. Shaw is an Associate Professor of Medicine in the Section of Infectious Diseases at Yale University School of Medicine.  A graduate of Harvard College and Harvard Medical School, Dr. Shaw trained with Philip Leder for his PhD in Genetics.  He completed his residency in Internal Medicine and fellowship in Infectious Disease at the Massachusetts General Hospital, and was a postdoctoral fellow in the laboratory of Fred Alt. 

Dr. Shaw’s graduate and postdoctoral research focused on the elucidation of signal transduction events controlling lymphocyte development in the immune system.  In establishing his own laboratory, he is directing his research efforts toward understanding the immunology of aging.  As a Brookdale National Fellow, Dr. Shaw studied the presenilin protein in B and T lymphocytes.  While mutations in presenilin have been implicated in familial forms of Alzheimer’s Disease, the function of presenilin in the immune system has remained incompletely understood.  Dr. Shaw employed a combination of genetic and biochemical approaches to define the role of presenilin in B and T cell development and function, with the goal of elucidating the potential consequences of presenilin mutations on the pathogenesis of Alzheimer’s Disease.  

Brookdale Fellow Class of 2003